The Hallmarks Of A Stem Cell - 1217 Words

The hallmarks of a stem cell are its ability to self-renew as well as its ability to differentiate and assume almost any cell fate if given the appropriate cues known as pluripotency (ref). The differentiation of stem cells requires large and rapid changes in gene expression. miRNAs are well suited to carry out this task through their ability to simultaneously inhibit the translation of several target genes allowing for coordinated control of cellular processes{Bartel:2009fh}. Furthermore, miRNAs have been shown to regulate embryonic development in addition to their role in regulating stem cell fate{Stefani:2008bw}. Evidence for this comes from experimental studies where the overall function of the miRNA biogenesis pathway was evaluated through genetic deletion of the miRNA processing enzymes DICER, DGCR8, Drosha, and AGO2. DICER knockout mice die at early stages of embryogenesis and fail to express the stem cell marker Oct4 and primitive streak marker T (brachyury), which respe ctively indicate a loss of stem cells and arrested development during gastrulation{Bernstein:2003dp}. Furthermore, DICER-deficient mouse ES cells are viable but incapable of differentiation, showing severe proliferation defects{Kanellopoulou:2005kf, Murchison:2005fa}. Similarly, DGCR8 knockout mice arrest early in development{Wang:2007gb}. DGCR8-deficient mouse ES cells also exhibit a proliferation defect and cannot efficiently silence the ES cell program, although these defects are not asShow MoreRelatedCancer : An Uncontrollable Division Of Cells1467 Words   |  6 Pagesdescribed as an uncontrollable division of cells. According to the National Cancer Institute, cancer is one of the leading causes of death in the world, with an estimated 595,690 deaths and 1,685,210 new cases in 2016 alone (NIH 2015). Cancer can develop from almost every organ of the body, with the most common organs affected being the breasts, lungs, prostate, colon, and bladder (NIH 2015). As the disease p rogresses, it may become metastatic, where the cancer cells migrate from their point of origin toRead MoreHuman Neural Stem Cell Tropism857 Words   |  4 PagesARTICLE TITLE: Human Neural Stem Cell Tropism to Metastatic Breast Cancer ESSAY TITLE: The Investigation of a therapeutic implication on metastatic breast cancer with a specialized human neural stem cell that is programed to secrete carboxylesterase combined with activated form of an ionotecan by targeting a specific tumor site and major cytokine involved in mediating susceptibility of neural stem cells to breast cancer cells. SCIENTIFIC SUMMARY: Metastatic Breast Cancer is characterized as aRead MoreInhibitory Effects Of Psoriasis In Mice797 Words   |  4 Pageschose to provide a summary of was one that examined the use of stem cells in order to decrease psoriasis in mice. The researchers specifically used Mesenchymal stem cells (MSCs), which are those found in the umbilical cord blood. They are multipotent and therefore are able to differentiate into many different types of tissues. These stem cells, in particular, have an â€Å"inhibitory effects on innate and adaptive immune cells† (Lee). The hallmark of a diagnosis of Psoriasis is the visible skin irritationRead MoreOverview Of Embryonic Stem Cells771 Words   |  4 PagesStem cells play a fundamental role during all stages of development and have the potential to study and treat disease (Spitalieri et al., 2016). Embryonic stem cells (ESC) are pluripotent cells that emerge from the inner cell mass of the blastocyst and can give rise to various cell types (Lian g and Zhang, 2013). Induced pluripotent stem cells (iPSC) have similar characteristics but are derived from adult differentiated somatic tissue (Liang and Zhang, 2013). This review will briefly compare ESC andRead MoreCell Abscission : The Final Step Of Cytokinesis1505 Words   |  7 Pages3.2 Cell abscission: the final step of cytokinesis After the division of nuclear membrane following duplicated chromosome segregation, in eukaryotic cell division, cytokinesis is carried out to divide a single cell into two daughter cells25. The process begins with the construction of a cleavage furrow intervened with actomyosin ring contraction3. The spindle midzone formed during anaphase gets transformed into intercellular bridge also known as the midbody responsible for connecting two new formingRead MoreSymptoms And Treatment Of Cancer1303 Words   |  6 Pagesmalignant neoplasm, the hallmark characteristic involves uncontrolled proliferation of cells. Under normal conditions cell grow, divide and die, but in cancer cells the defect takes place at the gene level leading to the formation of an abnormal DNA. As genes are the basic control machines of the cell, alteration of any kind may bring devastating consequences, or malignancy. Moreover, in normal cells damage of any kind is taken care by the repair system but in cancer cells , the repair function isRead MoreThe Importance Of Stem Cell Research805 Words   |  4 Pageshereditary altering. In stem cell research, â€Å" An isogenic human iPSC cell line precisely corrected by the CRISPR-Cas9 system was recently constructed, despite the handling difficulties associated with gene editing of human stem cells† (Kim, â€Å"CRISPR-Cas9: a promising tool for gene editing on induced pluripotent stem cells.†) iPSCs, which are fundamentally the same as embryonic stem cells, are pluripotent cells with a high self-reestablishment rate that can separate into all cell sorts; be that as itRead MoreThe Aging Process And Key Diseases Associated With Aging2223 Words   |  9 Pagesin the adoption of innovative treatments and declined risk for older adults. In order to better understand aging-associated diseases, it is first necessary to define what aging is. Aging is a complex, multifactorial process of harmful mutations in cells and tissues that are accumulated over time and result in an increased risk of disease and, eventually, death (Tosato, Zamboni, Ferrini, Cesari, 2007, p. 401). Contrary to the belief that aging can be cured through medical advances, it is scientificallyRead MoreInduction, Molecular Mechanisms And Consequences Of EMT1519 Words   |  7 Pagesthe activation of intracellular signaling cascades in the tumor cells. The stromal signals capable of inducing an EMT in epithelial cells include (a) several key signaling molecules such as TGF-s, Notch and Wnt, (b) activation of receptor tyrosine kinases (RTKs), (c) matrix metalloproteinases (MMPs), (d) hypoxia and (e) inflammatory signals (Polyak and Weinberg, 2009). Together with genetic and epigenetic alterations of the cancer cell genome, they can induce the expressi on of pleiotropically actingRead MoreThe Is The Uncontrolled Growth Of Blood Cancer New Zealand1609 Words   |  7 PagesLeukaemia is the uncontrolled growth of blood cells which occurs in the bone marrow (National Cancer Institute, 2013). Every day six New Zealanders are diagnosed with some form of blood cancer (Leukaemia and blood cancer New Zealand, 2015). It is believed that more than 10,000 people in New Zealand are affected by blood cancers such as, leukaemia, lymphoma or myeloma or related blood diseases (Leukaemia and blood cancer New Zealand, 2015).Leukaemia is believed to be ten times more common in adults

Terrorism Essay - 623 Words

nbsp;nbsp;nbsp;nbsp;nbsp;A gunshot, an explosion, and screaming heard. That is what is generally thought of when one hears the word quot;Terrorismquot;. In most cases it is true, but there are many other types of terrorism. Most terrorist incidents in the United States have been bombing attacks, involving explosive devices, tear gas and pipe bombs. (Collins, B. 1)The Federal Bureau of Investigation (FBI) categorizes terrorism in the U.S. as either; domestic or international terrorism. Terrorism is the use of force or violence against persons or property in violation of the criminal laws of the United States for purposes of intimidation, coercion or ransom. Terrorists often use threats to create fear among the public, to try to†¦show more content†¦1) nbsp;nbsp;nbsp;nbsp;nbsp;Besides individual leadership into terrorism, the KGB was a recent group of leaders that would intimidate any anti-soviet behavior, by the way of interrogation and trial of any suspects that they considered suspicious. The KGB handled internal functions such as surveillance of the Soviet population to make sure that everyone was loyal to its country. (Quaide, D. 1) nbsp;nbsp;nbsp;nbsp;nbsp;Terrorism can be classified in many ways, from destruction of buildings, to destroying or invading of computers. The face of technology has changed the way terrorist carry out their acts, while the intentions are still the same. The intelligence systems, security, procedures, and equipment that were once expected to protect the U.S. people, are now becoming powerless against this new type of technology. nbsp;nbsp;nbsp;nbsp;nbsp;Individual terrorism has many forms such as hijacking of commercial airplanes or cruise ships. But the most recent, frequent type throughout the U.S. consists of Bomb-mobiles or vehicles loaded with explosives to be used in residential areas.(Hancock, L. 2) The terrorist act at the Federal Building in Oklahoma City left 169 adults and children dead and the entire city in trauma. (Collins, B. 1) nbsp;nbsp;nbsp;nbsp;nbsp;The Uni-Bomber was another well known terrorist. He used homemade explosives to package boxes so when the victim opened it, he wasnt supposed to live. He targeted individuals as well asShow MoreRelatedTerrorism : Terrorism And Terrorism1326 Words   |  6 Pagesallowing terrorism to be successful and continue. Terrorists gain power through the common, innocent people they attack. How the world responds to terrorist attacks determines whether or not terrorism will cease. The common people’s response to terrorism, the interest of the state, and the media’s role in terrorism all aide to terrorism’s success and its continuation in the future. How people willingly choose to respond to terrorist attacks defines terrorism and determines if terrorism will continueRead MoreTerrorism : Terrorism And Terrorism1035 Words   |  5 PagesOver the past Century, terrorism has advanced from random killings to enormous plans for terrorist groups. To understand terrorism you must first define it. Terrorism as we all know it is hard to define and understand, and has many different definitions as it is used widely. The word terrorism stems from the word terror, which means to instill fear in. People become terrorists when they take the actions towards instilling fear and terror upon people to prove a certain point or agenda. Some terroristsRead MoreTerrorism : Terrorism And Terrorism1626 Words   |  7 PagesTerrorism can be categorized as â€Å"the use of intentionally indiscriminate violence as means to create terror, or fear, to achieve a political, religious, or ideological aim (Fortna).† Although there is no formal definiti on of terrorism, we typically associate the words terrorism and terrorists with acts of violence that are used unlawfully to intimidate in pursuance of political gain. Terrorists do not act at random, but rather use violence to maximize on fear and publicity with a specific goal inRead MoreTerrorism : Terrorism And Terrorism1126 Words   |  5 PagesTerrorism Have you ever had a fear for your family, your town, your country, or your world. How about the fear to have everything taken from you, destroyed, and not caring if it has hurt you or not? What about your fear and pain is, and can be someone else’s happiness? The fear of you being terrorized? That is terrorism. Someone else bringing fear and terrorizing you. That is a terrorist’s goal. Terrorism is common and is very difficult to stop. The government promises protection for the peopleRead MoreTerrorism And Terrorism : Terrorism1231 Words   |  5 Pages Terrorism is a common term used in the media and news everyday, especially in the United States. We are in a constant battle against ‘terrorism’, â€Å"Counterterrorism has to be woven into the everyday workings of every department. It should be included on the agenda of every meeting†¦Ã¢â‚¬  (Kelling Bratton, 2006). Terrorism and How to Respond All terrorism is criminal but not all criminals are terrorists. Terrorism unlike most crimes has a political agenda behind it. Many terrorists are involved withRead MoreTerrorism : Terrorism And Terrorism851 Words   |  4 PagesTerrorist attacks are major threats that could occur in any nation. Terrorism is one of those things that can happen at any time. It will strike in small, medium and large cities. Although we will never be able to remove all risk from terrorism, we can definitely reduce the risk through hazard mitigation and disaster preparedness (GBRA, 2011). To better understand terrorism we need to know what it is. Terrorism can be defined as the use of force or violence against persons or property in violationRead MoreTerrorism : Terrorism And Terrorism1377 Words   |  6 PagesTerrorism in Sudan In the past, Sudan had been designated as a State Sponsor of Terrorism regarding support for international terrorist groups. However, Sudan has changed its approach ever since the 9/11 attacks has been aiding the United States in diminishing the pervasiveness of terrorist groups in Sudan, and in the world. Recently, Sudan has remained cooperative with the United States in its war on counter terrorism. Sudan has taken many preventive measures to keep these terrorist groups outRead MoreThe Effects Of Terrorism On Terrorism And Terrorism944 Words   |  4 PagesEffects of Terrorism â€Å"The history of terrorism is a history of well-known and historically significant individuals, entities, and incidents associated, whether rightly or wrongly, with terrorism,† (History of Terrorism). The history of terrorism is a long bloody road. One of the bloodiest of acts of terrorism in the early years, was the reign of terror. In which, the Jacobin leader, Maximilien Robespierre, executed 40,000 people. Newspapers coined the word â€Å"Terrorism† as a way of describing RobespierreRead MoreTerrorism Between Terrorism And Terrorism1207 Words   |  5 PagesQuestion † What trends are evident in terrorism over the past 5 years? How have these trends impacted on the ways in which counter terrorism has responded in the Australian context? Introduction Terrorism poses a serious security challenge to the Australia and globally as it prevalence has increased over a decade although less attacks occur in the Western nations. The purpose of this assignment is to examine what trends and terrorist tactics are evident internationally over the past 5 years andRead MoreTerrorism Between Terrorism And Terrorism2012 Words   |  9 PagesTerrorism has played a brutal and alarming role in societies across the world. Many nations have been confronted with the need to develop solutions in the wake of tragedies caused by terrorism. Unfortunately, terrorist organizations are still operating and terrorist acts have continued. Many questions that have still gone unanswered despite careful study, but governments are finding some relief when collaborating with anti-terrorism organizations (Fischer, 2002). Terrorists have struck almost everywhere

Why is college important Free Essays

Everyone in the United States wants to achieve the â€Å"American Dream†. People want to be able to provide a stable lite tor their families. A college education has been a must to grow in the work industry. We will write a custom essay sample on Why is college important or any similar topic only for you Order Now But during this economic recession, college students have been having a difficult time staying in the college path, especially working class students. The lack of moral support from their families prevents these unfortunate students to finish their college education. The increase of college tuition and limited financial ald are causing students to go Into debt, making them hesitant hether they should keep studying or not. Also it’s preventing students from picking needed major but because the low paycheck they are not sure if they will be able to be sustained. But college drop outs also can able be due to the unequal college preparation given in high schools. The education system needs to be reformed so students have the opportunity to choose whether they want to go to college or do vocational tralnlng Instead. A college degree Is bringing more negauve aspects Into a student’s life therefore students, especially from working class. must know the alternatives to be able to succeed. Most ot the students In the united states are middle or working class. In addltlon of going to school, working class students also have to get a Job to be able to help out their families. Working class students have always struggled to get by during their years in college but most ot these students have families who support their dreams of coming out of poverty and become somebody with no pressures However there are also students who lack family support and deal with these issues alone throughout college. According to the New York Times article For Poor, Leap to College Often Ends in a Hard Fall, â€Å"Likely reasons [that low income students drop out of college] include soaring Incomes at the top and changes in family structure, which have left fewer low-income students with the support of two-parent homes†. These working class students have to find out their way out of college by themselves, sometimes feeling isolated and Intlmlddted by the system. Feeling under the pressure of obtaining a college degree to benefit their families they find themselves often in debt, not knowing about other options out there. Congress should start more unding towards higher education so students who truly want to conunue with college can do so without increasing their debts, Due budget cuts In education, the amount of financial aid is limited for students therefore it is more difficult to pay for their education. In the past decade college tultlon fees have been Increasing and soon enough students are not being able to receive full financial aid for their college education. Financial aid is supposed to help those students who fall below the poverty line, but since the recession hit the united states more middle class students re finding themselves in a bad situation. In the article No Aid for You: Cheating the Middle Class, Jennifer Hutchinson says â€Å"Due to this large increase In tuition, middle class families can no longer attord to pay tor their child’s education, putting them in the same situation as the low-income students†. Not qualifying for grants these students take tne oTTerea loans ana every year tne amount 0T aeot Increases. Hutchinson also states that â€Å"However, unlike low-income students†¦ who could not afford college, instead of going out into the workforce after graduation, middle-class tudents are now expected to go on to college†. Nowadays a college degree is needed to get a decent paying Job and the competition for Jobs is increasing among the young college graduates. If the financial aid system is not reformed soon there is going to be more students having to leave their college education behind when no longer can go into debt. College should become cheaper so the students won’t have to choose between their passions versus their stability. With their debts increasing every year students are researching if their majors are worth it to pay back their debts and be able to sustain them. According to the State Public Interest Research Group’s Higher Education Project, â€Å"23 percent of students who graduate from public universities would face unmanageable debt burdens if they entered teaching based upon average starting salaries. † Loans are causing college students to stay away from majors that won’t have a beneficial because these majors will not have an income strong enough to hold on to. Although these students want to study something that will essentially benefit the whole society they won’t be able to do so unless there is a change in the college system. Even though students are told they have to go to college, students are often found to give up as soon as they walk in the campus because they feel they are not ready for college. They try to take classes but they leave feeling overwhelmed by either the content of the class or their lack of enthusiasm to be in the classroom. In the article Why Do So Many Americans Drop Out of College? Jordan Weissman says â€Å"But once they get to class, not every student is prepared. Nor do they necessarily want to be at college, or have a clear notion of what they’re doing there†¦ The economy is screaming that they need a degree. But once on campus, they don’t last. † These students do not have an idea of what to make of their college education and waste resources such as classes and funds. Colleg e preparedness should start since high school. Students should also know if they are ready to take on the challenge of a college education. There should be a tougher way for students to be selected into four year institutions. Colleges should be stricter with grades once students reach high school. Also there is the importance of high school counselors working with students to help them find out what they truly want to do ith their life. It could help them decide if college is a place they want to be at or instead seek vocational training after high school, preventing students dropping out of college and insures that those obtaining a vocational training gain the skills to enter the work force. Students have to know the other options out there besides college. The United States needs to establish more vocational schools so that those who choose not to go to college can also succeed in the work force. As many other countries have shown, vocational training can be beneficial to the whole society. The vocational schools we ave already have shown to be mostly effective for those people who need a Job fast to sustain their families. By being able to get hands-on training, these students have more ability to qualify for a Job right away than a college graduate because they have experience in that certain field. According to the article The Secret To Germany’s Low Youth Unemployment â€Å"Germany’s youth employment is the highest in Europe†¦ At the neart 0T tnat success Is a learn-on-tne-JoD apprentlcesnlp system tnat nas I ts roots In the Middle Ages but is thriving today in Germany’s modern, export-oriented conomy’. These students can choose between a vocational or academic career though many chose the vocational training. Through internships, the youth are in training earning weekly wages. In order for the United States to become successful in recovering from the recession more vocational schools have to be implemented around the country so there can be equal opportunities for those who do not want to go to college. The college system in the United States needs work. Students are feeling lost without moral support from their families. Limited financial aid is forcing more low nd middle class students to go into debt in order to continue their college education. High schools need to start preparing their students for the years ahead in college. But most importantly it is showing that college is not the only option available for students who know they cannot make it through the years. People need to start realizing that college is not for everyone and that vocational schools can be a positive way to increment work force in this country. Vocational schools are also successful in creating educated people. In the long run there will be a positive outcome for students in their future lives. How to cite Why is college important, Papers

If it be friendship that you desire, then I am re Essay Example For Students

If it be friendship that you desire, then I am re Essay ady for itbut to be your subject, that I cannot be. As quoted by The famous quote of Chief Machemba, who resisted European conquest along with his tribal community. Throughout the 19th century, the powers of Europe sought control over Africa. The countries like Portugal, Great Britain, France, Belgium, Germany, Spain and Italy were involved in the colonization of Africa for the abundant resources that were available then. At the end of 1912 the only states in Africa that werent colonized were Liberia and Ethiopia. Liberia and Ethiopia were the only countries that werent colonized in the vast African continent. The conquest impacted the daily lives of African people relinquishing their resources. We will write a custom essay on If it be friendship that you desire, then I am re specifically for you for only $16.38 $13.9/page Order now In conclusion, European imperialism in Africa had many negative effects. Africa was devastated by the wrath of the European empires, however the power of these nations stretched around the world. Europeans caused many negative problems in Africa. Many Africans, at that time felt that the Europeans got more out of imperialistic laws than they did, for example many Africans were treated poorly, but most of them were transported to other nations where they were subjugated to slavery with no freedom and separated from families. The Europeans saw themselves as superior over other races and wanted the cultures of these people to assimilate into their superior one, as they believed that the Europeans tried to change the religion, the language and the way of life of the colonized people, which shows how Europeans had little respect for native culture and customs. In addition, the colonial people had no control over their government or their countrys resources. Since, the European countries w ere often in conflict with one another, they stripped their colonies of their resources to fuel their might, which has made many African countries very poor. , In fact, the nominal gdp for all of Africa combined is less than that of Germany They also created division between the African tribes, which we all witnessed in the Rwandan genocide. This happened even decades after they left in the 1980s because the Belgians placed Tutsis in power over the Hutus. The Hutus were angered by the mistreatment, revolted and mass murdered the Tutsis killing about 500 000 to 1 000 000. As more of the Europeans came to Africa, they brought diseases like smallpox with them. The African people werent immune to this disease, which killed many. Also, most of Africa was stripped of its resources. However, in some cases, imperialism benefited the people of Africa. For example, missionaries caught attention of the African people by showing their generosity and their ways of Christianity. They built school s and medical clinics along churches by which the Africans received health benefits as well as but also education. Over 800 different languages approximately known during the 1870s and only 5 common languages were soon spoken by many Africans because of the missionaries who opened schools along with churches. In addition, imperialism also brought jobs and industry to the colonies and it introduced the ideas of constitutional government to the Africans. Imperialism is the total domination of the political, economic, or cultural aspects or a nation. Imperial colonization has been occurringsensethe beginning of time. An imperialistic nation would increase its importance and power by winning an empire. Some takeovers were forced by political rivalries. One nation might seize a territory to prevent a competitor from expanding into that region. Some nations would expand to boost their economic value, or personal wealth. Imperialism advances a countries politics, society, and economic val ue into a powerful money-making country.The political aspect of imperialism progresses a country from beingweekinto a strong fighting nation. For example, when the French were taking over parts of Africa, the communication ofthe two countriesincreased and they started to share the Suez Canal. Also, when the British government set up a system of Colonial rule, it controlled over 280 million Indians. Thus, encouraging officials to learn new languages. When the Spanish took over Latin America they constructed a Council of the Indies which issued over 400,00 orders to improve the cities. However,without society, politics would have gotten nowhere.The social aspect of imperialism was very important. First, by the colonization of countriesscientist could find causes and treatments to diseases such as malaria and yellow fever. Also, Britain built canals, roads, and railways which opened Indias interior. The Spanish improved the Aztecs cities by making public waterways, paved and lighted st reets, and an invention the printing press. The society increased but when it enhanced the economics boosted also.The economics of imperialism is a major reason why nations would take over other countries. InAfricathey introduced better farming techniques like dykes and irrigation canals, which boosted the money growth. The British improved medical care that includeddoctor education, thus leading into a boom in the population. The Spanish exported crops and raw materials, making fortunes for the new government.In conclusion, imperialism is a vehicle of advancement. This promotion is brought to countries that arent strong enough to defendthem selves. In most cases,the economic value of the new country will increase. Therefore,imperialism advances a countries politics, society, and economic value into a powerful money making country. .ue2588bb5a38d60abaaa31c3e2520f5fc , .ue2588bb5a38d60abaaa31c3e2520f5fc .postImageUrl , .ue2588bb5a38d60abaaa31c3e2520f5fc .centered-text-area { min-height: 80px; position: relative; } .ue2588bb5a38d60abaaa31c3e2520f5fc , .ue2588bb5a38d60abaaa31c3e2520f5fc:hover , .ue2588bb5a38d60abaaa31c3e2520f5fc:visited , .ue2588bb5a38d60abaaa31c3e2520f5fc:active { border:0!important; } .ue2588bb5a38d60abaaa31c3e2520f5fc .clearfix:after { content: ""; display: table; clear: both; } .ue2588bb5a38d60abaaa31c3e2520f5fc { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .ue2588bb5a38d60abaaa31c3e2520f5fc:active , .ue2588bb5a38d60abaaa31c3e2520f5fc:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .ue2588bb5a38d60abaaa31c3e2520f5fc .centered-text-area { width: 100%; position: relative ; } .ue2588bb5a38d60abaaa31c3e2520f5fc .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .ue2588bb5a38d60abaaa31c3e2520f5fc .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .ue2588bb5a38d60abaaa31c3e2520f5fc .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .ue2588bb5a38d60abaaa31c3e2520f5fc:hover .ctaButton { background-color: #34495E!important; } .ue2588bb5a38d60abaaa31c3e2520f5fc .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .ue2588bb5a38d60abaaa31c3e2520f5fc .ue2588bb5a38d60abaaa31c3e2520f5fc-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .ue2588bb5a38d60abaaa31c3e2520f5fc:after { content: ""; display: block; clear: both; } READ: Christina Harwood Essay INCLUDEPICTURE http://www.planetpapers.com/images/btn-sign-in-full-essay.png * MERGEFORMATINET